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Lysine demethylase 5C inhibits transcription of prefoldin subunit 5 to activate c-Myc signal transduction and colorectal cancer progression.

Fulong YuLiang LiYimei GuSong WangLianbang ZhouXiaohu ChengHeng JiangYang HuangYingfeng ZhangWenbao QianXianghua LiZhining Liu
Published in: Molecular medicine (Cambridge, Mass.) (2024)
This study demonstrates that KDM5C inhibits PFDN5 transcription, thereby activating c-Myc signal transduction and promoting CRC progression.
Keyphrases
  • transcription factor
  • signaling pathway
  • protein kinase