Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue.

Pascual TorresOmar Ramírez-NúñezRicardo Romero-GuevaraGisel BarésAna B Granado-Serrano Victòria Ayala Jordi BoadaLaia FontdevilaMonica PovedanoDaniel Sanchis Reinald Pamplona Isidro Ferrer Manuel Portero-Otin

Published in: Autophagy (2018)

ALS: amyotrophic lateral sclerosis; ATG4B: autophagy related 4B cysteine peptidase; AUC: area under the curve; FTLD: frontotemporal lobar degeneration; iPSC: induced pluripotent stem cells; ROC: receiver operating characteristic; TARDBP: TAR DNA binding protein; RT-qPCR: quantitative RT-PCR.

Keyphrases

amyotrophic lateral sclerosis
induced pluripotent stem cells
binding protein
cell death
endoplasmic reticulum stress
signaling pathway
oxidative stress
circulating tumor
high resolution
single molecule
fluorescent probe
nucleic acid