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The Association of Brain Insulin Resistance with Anesthesia/Surgery-Induced Cognitive Deterioration Is Female-Specific in 5XFAD Transgenic Mice.

Junyao ZhangYinglin ZhangYingying ZhangJunyan Yao
Published in: Journal of Alzheimer's disease : JAD (2024)
This study demonstrated that female 5XFAD Tg mice were more susceptible to anesthesia/surgery-induced cognitive deterioration and tau pathology aggravation, potentially due to female-specific brain insulin resistance.
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