Sesamol Mitigates Chronic Iron Overload-Induced Cognitive Impairment and Systemic Inflammation via IL-6 and DMT1 Regulation.
Yajie WangYuyu ZhangXinyu WangQingyuan LiYu ZhaoYishan JiangRui GuoXuebo LiuTian YuanZhigang LiuPublished in: Molecular nutrition & food research (2023)
These findings suggest that sesamol may be effective in mitigating neuroinflammatory responses and cognitive impairments induced by iron overload, potentially through its involvement in mediating the liver-brain axis.