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Newly Diagnosed Sarcopenia and Alzheimer's Disease in an Older Patient With Chronic Inflammation.

Sun-Hyung KimDeok Su SinJae-Young Lim
Published in: Annals of geriatric medicine and research (2019)
A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer's disease. Low-grade chronic elevation of inflammatory markers was also revealed. We assumed that chronic low-grade inflammation with aging, also called "inflammaging," contributed to the development of multiple comorbidities. After multidisciplinary treatment and comprehensive rehabilitation, he could ambulate again with minimal to moderate assistance. Various age-related disorders should be suspected when older patients present with chronic low-grade inflammation.
Keyphrases
  • low grade
  • high grade
  • oxidative stress
  • newly diagnosed
  • cognitive impairment
  • skeletal muscle
  • cognitive decline
  • physical activity
  • case report
  • high intensity
  • quality improvement
  • combination therapy