Sec61γ is a vital protein in the endoplasmic reticulum membrane promoting tumor metastasis and invasion in lung adenocarcinoma.

Shanqi XuXin LiJianxiong GengYingyue CaoYan Yu Lishuang Qi

Published in: British journal of cancer (2023)

Sec61γ promoted the proliferation, metastasis, and invasion of LUAD through EGFR pathways. Sec61γ might be a potential target for the treatment of LUAD metastases.

Keyphrases

endoplasmic reticulum
cell migration
small cell lung cancer
epidermal growth factor receptor
signaling pathway
tyrosine kinase
protein protein
combination therapy
binding protein
human health