HLA Class I association with autoimmune diabetes in Chinese: Distinct implications in classic type 1 diabetes and LADA.

Ying XiaYan ChenXia LiShuoming LuoJian LinGan HuangYang XiaoZhiying ChenZhiguo Xie Zhiguang Zhou

Published in: The Journal of clinical endocrinology and metabolism (2023)

The attenuated HLA class I susceptibility to LADA was indicative of a less deleterious immunogenetic nature compared with classic T1D. These autoimmune diabetes-related Class I variants might serve as additional markers in future screening among Chinese.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
multiple sclerosis
insulin resistance
drug induced
current status
copy number
gene expression
metabolic syndrome
genome wide