Analysis of colistin resistance in carbapenem-resistant Enterobacterales and XDR Klebsiella pneumoniae .
Raunak BirHitender GautamNazneen ArifPriyanka ChakravartiJyoti VermaSayantan BanerjeeSonu TyagiSarita MohapatraSeema SoodBenu DhawanRama ChaudhryArti KapilBimal Kumar DasBhabatosh DasPublished in: Therapeutic advances in infectious disease (2022)
The performance of cBMD was excellent, whereas the E-test was unacceptable. VITEK-2 and RPNP performed better but remained unreliable due to high error rates. Multiple mutations in the target proteins involving lipopolysaccharide formation, modification, and regulation were seen, resulting in colistin resistance.