Long-Term Effects of Angiotensin Receptor-Neprilysin Inhibitors on Myocardial Function in Chronic Heart Failure Patients with Reduced Ejection Fraction.

Gregor PoglajenAjda Anžič-DrofenikGregor ZemljičSabina FrljakAndraž CerarRenata OkrajšekMiran ŠebeštjenBojan Vrtovec

Published in: Diagnostics (Basel, Switzerland) (2020)

ARNI therapy appears to improve echocardiographic parameters of left and right ventricular function in HFrEF patients above the effect of pre-existing optimal medical management. These effects may be particularly pronounced in patients with nonischemic heart failure, LVEF < 30% and lower degree of neurohumoral activation.

Keyphrases

ejection fraction
heart failure
left ventricular
end stage renal disease
newly diagnosed
healthcare
prognostic factors
mitral valve
cardiac resynchronization therapy
peritoneal dialysis
atrial fibrillation
patient reported outcomes
mesenchymal stem cells
left atrial
angiotensin converting enzyme
smoking cessation