Chemical metabolome assay by high-resolution Orbitrap mass spectrometry and assessment of associated antitumoral activity of Actinocephalus divaricatus.
Ana Caroline ZanattaAngela MariMilena MasulloIracilda Zeppone CarlosWagner VilegasSonia PiacenteLourdes Campaner Dos SantosPublished in: Rapid communications in mass spectrometry : RCM (2018)
The HRMS technique enabled us to identify several classes of compounds. In addition, saponins were identified for the first time in plants belonging to the Eriocaulaceae family. Thus, the essential contribution of this work lies in the new elements it brings to the taxonomic discussion which the Actinocephalus genus as a distinct genus of the Paepalanthus. The results obtained show that the methanolic extract of the capitula could be a promising source of bioactive fractions and/or compounds that may contribute towards breast cancer treatment.
Keyphrases
- high resolution
- mass spectrometry
- liquid chromatography
- high resolution mass spectrometry
- gas chromatography
- tandem mass spectrometry
- high performance liquid chromatography
- ultra high performance liquid chromatography
- oxidative stress
- capillary electrophoresis
- high throughput
- anti inflammatory
- high speed
- simultaneous determination
- ms ms
- solid phase extraction