Association of white matter hyperintensities with long-term EGFR-TKI treatment and prediction of progression risk.

Hang YangRui MengJunjie JiangYan LuoXiaolin DengSibo YangShengcai ChenJiehong WuYan WanYanan LiHuijuan JinQuanwei HeDavid WangJiang ChangKunyu YangYifan ZhouBo Hu

Published in: Brain and behavior (2023)

Patients with NSCLC who received EGFR-TKI may be at higher risk of developing WMH or worsening of WMH burden. The impact of increased WMH lesions in these patients is to be further assessed. IL-2, IL-4, and IL-10 may be used as potential biomarkers to monitor the risk of increased WMH burden.

Keyphrases

tyrosine kinase
small cell lung cancer
epidermal growth factor receptor
advanced non small cell lung cancer
white matter
end stage renal disease
newly diagnosed
ejection fraction
risk factors
multiple sclerosis
combination therapy
patient reported