Serotonin-Related Gene Variants in Patients with Irritable Bowel Syndrome and Depressive or Anxiety Disorders.

Magdalena GrzesiakJan Aleksander BeszłejEwa WaszczukMarcin SzechińskiMonika Szewczuk-BogusławskaDorota FrydeckaTadeusz DoboszAnna JonkiszArleta LebiodaMałgorzata MałodobraAgata Mulak

Published in: Gastroenterology research and practice (2017)

Our results provide further evidence for the involvement of SLC6A4 rs4795541 and HTR2A rs6311 polymorphisms in the pathophysiology of depressive disorders in IBS patients. The new findings indicate that HTR2C rs6318 polymorphism may be associated with the susceptibility to anxiety disorders in IBS patients.

Keyphrases

irritable bowel syndrome
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
copy number
stress induced
dna methylation