Sleep disturbance and memory dysfunction in early multiple sclerosis.

James F SumowskiSam HorngRachel BrandstadterStephen KriegerVictoria M LeavittIlana Katz SandMichelle FabianSylvia KlineovaRobin GraneyClaire S RileyFred D LublinAaron E MillerAndrew W Varga

Published in: Annals of clinical and translational neurology (2021)

Sleep disturbance contributes to MS memory dysfunction, which may help explain differential risk for memory dysfunction in persons with MS, especially since sleep disturbance is common in MS. Potential mechanisms linking sleep disturbance and memory are discussed, as well as recommendations for further mechanistic and interventional research.

Keyphrases

multiple sclerosis
working memory
sleep quality
mass spectrometry
physical activity
ms ms
oxidative stress
white matter
risk assessment