Eco-Friendly Stability-Indicating HPLC Method for Related Compounds in Pemetrexed Ditromethamine (Antineoplastic Agent) for Injection.
Arjuna Rao NekkalapudiSrinivasu NavuluriSreenivas PippallaPublished in: Journal of AOAC International (2024)
The developed liquid chromatographic method greenness and eco-friendliness were assessed using the green analytical procedure index (GAPI) and the analytical greenness (AGREE) tool, and found to be green. A PDT detoxification procedure was also developed to reduce environmental pollution.
Keyphrases
- simultaneous determination
- small cell lung cancer
- liquid chromatography
- minimally invasive
- ms ms
- human health
- heavy metals
- risk assessment
- photodynamic therapy
- mass spectrometry
- particulate matter
- tandem mass spectrometry
- high performance liquid chromatography
- ionic liquid
- ultrasound guided
- advanced non small cell lung cancer
- high resolution
- drinking water
- tyrosine kinase
- water quality