Non-invasive measurement of retinal permeability in a diabetic rat model.
Claire L AllenNaseeb K MalhiJacqueline L WhatmoreDavid Owen BatesKenton P ArkillPublished in: Microcirculation (New York, N.Y. : 1994) (2020)
This novel imaging methodology in combination with mathematical quantification allows retinal permeability to be non-invasively and accurately measured at multiple time points in the same animal. In addition, this technique is a non-toxic, rapid, sensitive, and cost-effective alternative to the Evans blue assay.