Rational design of cancer gene panels with OncoPaD.
Carlota Rubio-PerezJordi Deu-PonsDavid TamboreroNuria Lopez-BigasNuria Lopez-BigasPublished in: Genome medicine (2016)
With its unique features, OncoPaD will help clinicians and researchers design tailored next-generating sequencing (NGS) panels to detect circulating tumor DNA or biopsy specimens, thereby facilitating early and accurate detection of tumors, genomics informed therapeutic decisions, patient follow-up and timely identification of resistance mechanisms to targeted agents. OncoPaD may be accessed through http://www.intogen.org/oncopad.
Keyphrases
- circulating tumor
- cell free
- circulating tumor cells
- single cell
- papillary thyroid
- case report
- genome wide
- squamous cell
- copy number
- high resolution
- loop mediated isothermal amplification
- cancer therapy
- ultrasound guided
- gene expression
- dna methylation
- lymph node metastasis
- single molecule
- young adults
- childhood cancer
- nucleic acid