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Impact of bronchoalveolar lavage lymphocytosis on the effects of anti-inflammatory therapy in idiopathic non-specific interstitial pneumonia, idiopathic pleuroparenchymal fibroelastosis, and unclassifiable idiopathic interstitial pneumonia.

Akira YamagataMachiko AritaHiromasa TachibanaFumiaki TokiokaChikatoshi SugimotoHiromitsu SumikawaTomonori TanakaHideki YasuiTomoyuki FujisawaYutaro NakamuraTakafumi SudaTadashi Ishida
Published in: Respiratory research (2021)
BAL lymphocytosis is associated with good outcomes in patients treated with anti-inflammatory drugs, but has no prognostic value when anti-inflammatory drugs are not used. BAL lymphocytosis may provide a predictive biomarker for identifying patients with iNSIP, iPPFE and unclassifiable IIP who are likely to benefit from anti-inflammatory drugs.
Keyphrases
  • anti inflammatory drugs
  • anti inflammatory
  • intensive care unit
  • bone marrow
  • adipose tissue
  • extracorporeal membrane oxygenation
  • glycemic control
  • replacement therapy