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A Regions of Interest Voxel-Based Morphometry Study of the Human Brain During High-Frequency Spinal Cord Stimulation in Patients With Failed Back Surgery Syndrome.

Sander De GrooteLisa GoudmanBengt LinderothFélix BuyckPhilippe RigoardMats De JaegerPeter Van SchuerbeekRonald PeetersStefan SunaertMaartens Moens
Published in: Pain practice : the official journal of World Institute of Pain (2020)
In patients with FBSS, high-frequency SCS influences structural brain regions over time. The volume of the hippocampus was decreased bilaterally after 3 months of high-frequency SCS with a positive correlation with back pain intensity.
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