Login / Signup

Multi-COBRA hemagglutinin formulated with cGAMP microparticles elicits protective immune responses against influenza viruses.

Xiaojian ZhangHua ShiDylan A HendyEric M BachelderKathryn M MooreTed M Ross
Published in: mSphere (2024)
Influenza viruses cause severe respiratory disease, particularly in the very young and the elderly. Next-generation influenza vaccines are needed to protect against new influenza variants. This report used a promising adjuvant, cyclic GMP-AMP (cGAMP), to enhance the elicited antibodies by an improved influenza hemagglutinin candidate and protect against influenza virus infection. Overall, adding adjuvants to influenza vaccines is an effective method to improve vaccines.
Keyphrases
  • immune response
  • early stage
  • gene expression
  • middle aged
  • dna methylation
  • toll like receptor
  • cystic fibrosis
  • genetic diversity