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Modeling Global Genomic Instability in Chronic Myeloid Leukemia (CML) Using Patient-Derived Induced Pluripotent Stem Cells (iPSCs).

Gladys TelliamChristophe DesterkeJusuf ImeriRadhia M'kacherNoufissa OudrhiriEstelle BalducciMicheline Fontaine-ArnouxHervé AcloqueAnnelise Bennaceur-GriscelliAli G Turhan
Published in: Cancers (2023)
These results demonstrated that we have generated, for the first time to our knowledge, an in vitro genetic instability model, reproducing genomic events described in patients with BC.
Keyphrases
  • chronic myeloid leukemia
  • induced pluripotent stem cells
  • copy number
  • healthcare
  • genome wide
  • dna methylation
  • gene expression