Impact of C-reactive Protein on Anticoagulation Monitoring in Extracorporeal Membrane Oxygenation.

Jai MadhokChristian O'DonnellJing JinClark G OwyangJonathan M WeimerRaymond A PashunYasuhiro ShudoJohn McNultyBlaine ChadwickStephen J RuossVidya K RaoJames L ZehnderJoe L Hsu

Published in: Journal of cardiothoracic and vascular anesthesia (2024)

Elevations in CRP are common during ECMO and can falsely prolong PTT measured by commonly used assays. The discrepancy due to CRP-interference is important clinically given narrow PTT targets and may contribute to hematological complications.

Keyphrases

extracorporeal membrane oxygenation
acute respiratory distress syndrome
respiratory failure
atrial fibrillation
venous thromboembolism
high throughput
risk factors
mechanical ventilation