Predictive factors for decreased baseline quality of life in patients with sinonasal malignancies.
Cara M FleseriuDaniel M BeswickSabrina L MaozPeter H HwangGarret W Choby GEdward Cheng-Lung KuanErik P ChanNithin D AdappaMathew GeltzeilerAnne E GetzIan M HumphriesChristopher H LeWaleed M AbuzeidEugene H ChangAria JafariTodd T KingdomMichael A KohanskiJivianne K LeeSeyed A NabavizadehJayakar V NayakJames N PalmerZara M PatelCarlos D Pinheiro-NetoAdam C ResnickTimothy L SmithCarl H SnydermanMaie A St JohnJay StormJeffrey D SuhMarilene B WangEric W WangPublished in: International forum of allergy & rhinology (2023)
Our findings demonstrate a negative impact on baseline QOL in patients with SNMs and suggest sex-specific and symptom-related lower QOL scores, with minimal histopathology association. Anatomical tumor involvement may be more reflective of QOL than T-staging, as orbital and skull base erosion, PNI, and palate lesions are significantly associated with reduced baseline QOL.
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