Evaluation of elastin fibres in young and aged eyelids and abdominal skin using computational 3D structural analysis.

We provide a novel 3D analysis method for elastin fibres and report age-related alterations in elastin fibre structure in the human eyelid and abdominal skin. This method contributes to the understanding of elastin fibre degeneration in more detail than conventional methods. Applying this 3D analysis method to skin tissues will contribute to a better understanding of age-related changes in fibres and to the development of novel wrinkle treatments.