VX-702 Ameliorates the Severity of Sepsis-Associated Acute Kidney Injury by Downregulating Inflammatory Factors in Macrophages.

Yue HanJingyi WangJin ZhangXi ZhengYijia JiangWei LiuWenxiong Li

Published in: Journal of inflammation research (2024)

VX-702 ameliorated S-AKI by inhibiting the release of proinflammatory cytokines from macrophages, indicating its potential as a novel therapeutic for S-AKI treatment.

Keyphrases

acute kidney injury
liver failure
intensive care unit
signaling pathway
oxidative stress
respiratory failure
mouse model
septic shock
combination therapy
extracorporeal membrane oxygenation
smoking cessation