Diagnostic performance of 18F-fluorodeoxyglucose positron emission tomography in the evaluation of glioma.
Tristan B ShawRosalind L JeffreePaul ThomasSteven GoodmanMaciej DebowskiZarnie LwinBenjamin ChuaPublished in: Journal of medical imaging and radiation oncology (2019)
The combination of FDG-PET/CT and gadolinium-enhanced MRI demonstrated marked improvement in identifying potential high-grade disease over each modality alone. Increased FDG uptake without gadolinium enhancement rarely occurred and identified high-grade histology in a small number of patients. Due to limited sensitivity and NPV, a negative FDG-PET/CT alone, or in combination with MRI, should not guide a decision for observation where surgery would otherwise be recommended.
Keyphrases
- positron emission tomography
- high grade
- computed tomography
- contrast enhanced
- pet ct
- low grade
- magnetic resonance imaging
- pet imaging
- end stage renal disease
- chronic kidney disease
- ejection fraction
- minimally invasive
- diffusion weighted imaging
- prognostic factors
- magnetic resonance
- coronary artery bypass
- patient reported outcomes
- percutaneous coronary intervention
- human health