Hematological disorders in children with Down syndrome.
Silvia TriaricoGiovanna TrombatoreMichele Antonio CapozzaAlberto RomanoStefano MastrangeloGiorgio AttinàPalma MauriziAntonio RuggieroPublished in: Expert review of hematology (2022)
In contrast to the excellent prognosis of ML-DS obtained likewise with low doses of chemotherapy, DS-ALL patients show worse outcomes than non-DS children, therefore advances and risk-stratified treatment adjustments are mandatory for this particular set of patients.