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Effectiveness, treatment completion and safety of sofosbuvir/ledipasvir and paritaprevir/ritonavir/ombitasvir + dasabuvir in patients with chronic kidney disease: an ERCHIVES study.

Adeel Ajwad ButtY RenA PuenpatomJ M ArduinoR KumarA-B Abou-Samra
Published in: Alimentary pharmacology & therapeutics (2018)
SOF/LDV and PrOD achieved high SVR rates in CKD population. Treatment completion rates were lower than expected. A decline in eGFR and development of anaemia were observed in a substantial proportion of persons, but the clinical implications remain unclear.
Keyphrases
  • hepatitis c virus
  • small cell lung cancer
  • systematic review
  • chronic kidney disease
  • epidermal growth factor receptor
  • combination therapy