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Outcomes of Kidney Transplant Patients with Atypical Hemolytic Uremic Syndrome Treated with Eculizumab: A Systematic Review and Meta-Analysis.

Maria L Gonzalez SuarezCharat ThongprayoonMichael A MaoNapat LeeaphornTarun BathiniWisit Cheungpasitporn
Published in: Journal of clinical medicine (2019)
This study summarizes the outcomes observed with use of eculizumab for prevention and treatment of aHUS recurrence in kidney transplantation. Our results suggest a possible role for anti-C5 antibody therapy in the prevention and management of recurrent aHUS.
Keyphrases
  • kidney transplantation
  • type diabetes
  • metabolic syndrome
  • skeletal muscle
  • mesenchymal stem cells
  • combination therapy
  • free survival
  • replacement therapy