The ghrelin agonist, HM01 activates central vagal and enteric cholinergic neurons and reverses gastric inflammatory and ileus responses in rats.
Pu-Qing YuanS Vincent WuLixin WangYvette TachéPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2023)
Peripheral HM0 activates central vagal and myenteric cholinergic pathways that may influence both central and peripheral targets to prevent AS-induced gastric inflammatory and ileus.