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Oral mucositis in childhood cancer patients receiving high-dose methotrexate: Prevalence, relationship with other toxicities and methotrexate elimination.

Jéssica Berté ValerMarina CurraAmanda de Farias GabrielTuany Rafaeli SchmidtMaria Beatriz Ferreira GurianRafael RoeslerJunior Mario Correa EvangelistaMarco Antonio Trevizani MartinsLauro Jose GregianinManoela Domingues Martins
Published in: International journal of paediatric dentistry (2020)
OM is a prevalent complication of childhood cancer patients receiving HD-MTX. Renal and hepatic toxicity could be considered risk factors for OM, especially in patients with lymphoma.
Keyphrases
  • childhood cancer
  • high dose
  • young adults
  • stem cell transplantation
  • low dose
  • risk factors
  • diffuse large b cell lymphoma
  • radiation induced
  • oxidative stress
  • radiation therapy