Effect of 28 days treatment of baricitinib on mechanical allodynia, osteopenia, and loss of nerve fibers in an experimental model of type-1 diabetes mellitus.

Rosa I Acosta-GonzálezAngélica Y Hernández-JiménezLaura Y Ramírez-QuintanillaHéctor F Torres-RodríguezVirginia M Vargas MuñozJuan Miguel Jiménez-Andrade

Published in: Pharmacological reports : PR (2024)

Our findings suggest that baricitinib may represent a new therapeutic alternative to treat T1DM-induced peripheral neuropathy and bone denervation.

Keyphrases

high glucose
diabetic rats
neuropathic pain
bone mineral density
metabolic syndrome
drug induced
soft tissue
oxidative stress
skeletal muscle
body composition
stress induced