ACAD10 is not required for metformin's metabolic actions or for maintenance of whole-body metabolism in C57BL/6J mice.

Michael J YewSarah E HeywoodJoe NgOlivia M WestMartin PalAndrew KuehGraeme I LancasterStephen MyersChristine YangYingying LiuSaskia ReibeNatalie A MellettPeter J MeikleMark A FebbraioDavid W GreeningBrian G DrewDarren C Henstridge

Published in: Diabetes, obesity & metabolism (2024)

Loss of ACAD10 does not alter whole-body metabolism or impact the acute or chronic metabolic actions of metformin in this model.

Keyphrases

liver failure
drug induced
respiratory failure
high fat diet induced
aortic dissection
intensive care unit
metabolic syndrome
adipose tissue
insulin resistance
wild type