Clinical relevance of intracranial hemorrhage after thrombectomy versus medical management for large core infarct: a secondary analysis of the SELECT2 randomized trial.
Michael ChenKrishna C JoshiBradley KolbClark W SittonDeep Kiritbhai PujaraMichael G AbrahamSantiago Ortega GutierrezScott E KasnerMuhammad Shazam HussainLeonid ChurilovSpiros BlackburnSophia SundararajanYin C HuNabeel HerialJuan F ArenillasJenny P TsaiRonald F BudzikWilliam HicksOsman KozakBernard YanDennis CordatoNathan W ManningMark ParsonsRicardo A HanelManuel Felipe GranjaTeddy WuPere Cardona PortelaChirag D GandhiFawaz Al-MuftiNatalia Perez de la OssaJoanna SchaafsmaJordi BlascoNavdeep SanghaSteven WarachTimothy John KleinigHannah JohnsFaris ShakerMohammad A AbdulrazzakAbhishek RayJeffery SunshineAmanda OpaskarKelsey R DuncanWei XiongFaisal K Al-ShaibiEdgar A SamaniegoThanh N NguyenJohanna T FifiStavropoula I TjoumakarisPascal M JabbourVitor Mendes PereiraMaarten G LansbergCathy SilaNicholas C BambakidisStephen DavisLawrence WechslerGregory W AlbersJames C GrottaMarc RiboAmeer E HassanBruce CampbellMichael D HillAmrou SarrajPublished in: Journal of neurointerventional surgery (2024)
ICH was present in 75% of the EVT population, but PH or sICH were infrequent. The presence of any ICH did not worsen functional outcomes or modify EVT treatment effect at 90-day follow-up. The high rate of hemorrhages overall still represents an opportunity for adjunctive therapies in EVT patients with a large ischemic core.