No drug holidays in BRAF V600E glioma patients: An argument for dose reduction of targeted therapies.

Danielle A BazerAnna KolchinskiNancy A O BushJennifer L ClarkeStephen J BagleyKarisa C Schreck

Published in: Neuro-oncology practice (2024)

Clinical and radiographic progression may occur rapidly upon holding BRAF-targeted therapy, warranting judicious dose reductions and minimization of drug holidays.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
metastatic colorectal cancer
emergency department
adverse drug
drug induced
wild type