No drug holidays in BRAF V600E glioma patients: An argument for dose reduction of targeted therapies.
Danielle A BazerAnna KolchinskiNancy A O BushJennifer L ClarkeStephen J BagleyKarisa C SchreckPublished in: Neuro-oncology practice (2024)
Clinical and radiographic progression may occur rapidly upon holding BRAF-targeted therapy, warranting judicious dose reductions and minimization of drug holidays.