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A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways.

Jörgen ÖstlingMarleen Van GeestHenric K OlssonSven-Erik DahlenEmilia ViklundPer M GustafssonEkaterina MirgorodskayaAnna-Carin Olin
Published in: Clinical proteomics (2022)
The applied analytical method was reproducible and allowed identification of pathologically interesting proteins in PEx samples from asthmatic subjects with high LCI. The results suggest that PEx based proteomics is a novel and promising approach to study respiratory diseases with small airway involvement.
Keyphrases
  • small molecule
  • cystic fibrosis
  • mass spectrometry
  • high throughput
  • lung function
  • label free
  • single cell