A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways.

Jörgen ÖstlingMarleen Van GeestHenric K OlssonSven-Erik DahlenEmilia ViklundPer M GustafssonEkaterina MirgorodskayaAnna-Carin Olin

Published in: Clinical proteomics (2022)

The applied analytical method was reproducible and allowed identification of pathologically interesting proteins in PEx samples from asthmatic subjects with high LCI. The results suggest that PEx based proteomics is a novel and promising approach to study respiratory diseases with small airway involvement.

Keyphrases

small molecule
cystic fibrosis
mass spectrometry
high throughput
lung function
label free
single cell