Course of subthreshold manic symptoms and related risk factors in the general population: A three-year follow-up study.

Rosalie A L BeekmanMargreet Ten HaveRon de GraafRalph W KupkaEline J Regeer

Published in: Bipolar disorders (2022)

This study supports the validity and clinical relevance of subM as a BD prodrome. It demonstrates that subM symptoms often persist or increase during follow-up and identifies 11 risk factors that are associated with an unfavourable course.

Keyphrases

risk factors
bipolar disorder
sleep quality
gene expression