OSCC cell-secreted exosomal CMTM6 induced M2-like macrophages polarization via ERK1/2 signaling pathway.

Xin PangSha-Sha WangMei ZhangJian JiangHua-Yang FanJia-Shun WuHao-Fan WangXin-Hua LiangYa-Ling Tang

Published in: Cancer immunology, immunotherapy : CII (2020)

OSCC cell-secreted exosomal CMTM6 induces M2-like macrophages polarization to promote malignant progression via ERK1/2 signaling pathway, revealing a novel crosstalk between cancer cells and immune cells in OSCC microenvironment.

Keyphrases

signaling pathway
pi k akt
single cell
epithelial mesenchymal transition
cell therapy
induced apoptosis
cell proliferation
stem cells
diabetic rats
endothelial cells
endoplasmic reticulum stress