New insights in HLA-E polymorphism by refined analysis of the full-length gene.
T I OlieslagersC E M VoorterM GroenewegYun-Ping XuL WietenM G J TilanusPublished in: HLA (2017)
Our study demonstrates that the nucleotide variability of the HLA-E gene is much higher than previously known, albeit in only a limited number of individuals. Overall only 2 variants, HLA-E*01:01 and *01:03, are frequently present worldwide, suggesting that balancing selection is acting on HLA-E.