Chronic Aichi virus infection as a cause of long-lasting multi-organ involvement in patients with primary immune deficiencies.

Jacques FourgeaudMathilde M LecuitPhilippe PérotJulie BruneauBeatrice RegnaultNicolas Da RochaMael BessaudCapucine PicardÉric JeziorskiBenjamin FournierRomain LevyAmbroise MarçaisStéphane BlanchePierre FrangeAlain FischerMarina CavazzanaAgnès FerroniAnne JametMarianne Leruez-VilleMarc EloitBénédicte Neven

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)

The similarity of the clinical presentation, the detection of AiV in a sub-group of patients suffering from immunodysregulation, its absence in asymptomatic patients, the detection of viral genome in infected organs by ISH, and the reversibility of symptoms after treatment argue for AiV causality.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
sars cov
gene expression
emergency department
dna methylation
electronic health record