The Spectrum of Dysregulated Aldosterone Production: An International Human Physiology Study.
Wasita W ParksookJenifer M BrownKei OmataYuta TezukaYoshikiyo OnoFumitoshi SatohLaura C TsaiYvonne NiebuhrJulia MilksAnna MooreBrooke HonzelHaiping LiuRichard J AuchusSarat SunthornyothinAdina F TurcuAnand VaidyaPublished in: The Journal of clinical endocrinology and metabolism (2024)
In the context of a low-renin phenotype, there is a continuum of primary aldosteronism and dysregulated aldosterone production that is prominently influenced by ACTH. A large proportion of individuals with low renin may benefit from aldosterone-directed therapy.