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ROS1 fusions in resected stage I-III adenocarcinoma: Results from the European Thoracic Oncology Platform Lungscape project.

Ernst-Jan M SpeelUrania DafniErik ThunnissenJan Hendrik RüschoffCathal O'BrienJacek KowalskiKeith M KerrLukas BubendorfIrene SansanoLeena JosephMark KriegsmannAtilio NavarroKim MonkhorstLine Bille MadsenJavier Hernandez LosaWojciech BiernatAlbrecht StenzingerAndrea RülandLisa M HillenNesa MartiMiguel A Molina-VilaTereza DellaportaRoswitha KammlerSolange PetersRolf A StahelStephen P FinnTeodora Radonicnull null
Published in: Lung cancer (Amsterdam, Netherlands) (2024)
The prevalence of ROS1 fusion in an LUAD stage I-III European cohort was relatively low. ROS1 IHC using SP384 clone is useful for exclusion of ROS1 gene fusion negative cases.
Keyphrases
  • cell death
  • dna damage
  • reactive oxygen species
  • palliative care
  • spinal cord
  • risk factors
  • genome wide
  • quality improvement
  • gene expression
  • copy number
  • high throughput
  • oxidative stress
  • transcription factor