Calcium-/Calmodulin-Dependent Protein Kinase II (CaMKII) Inhibition Induces Learning and Memory Impairment and Apoptosis.

Jialu WangXiaoxue XuWanying JiaDongyi ZhaoTomasz BoczekQinghua GaoQianhui WangYu FuMiao HeRuixue ShiXin TongMeixuan LiYu TongDongyu Min Wuyang Wang Feng Guo

Published in: Oxidative medicine and cellular longevity (2021)

CaMKII inhibition caused learning and memory impairment and apoptosis, which might be related to dysregulated JNK signaling.

Keyphrases

protein kinase
cell death
endoplasmic reticulum stress
cell cycle arrest
oxidative stress
induced apoptosis
signaling pathway
cell proliferation