EIF4A3-negatively driven circular RNA β-catenin (circβ-catenin) promotes colorectal cancer progression via miR-197-3p/CTNND1 regulatory axis.

Li-Qiang DengChuan-Jian ShiShu-Ting ZhouWei-Qiang ZengYan-Fang XianYu-Yan WangWei-Ming FuHan-Li Lin Wei Liu Jin-Fang Zhang

Published in: British journal of cancer (2024)

Our findings illustrated a novel mechanism of circβ-catenin in modulating CRC tumorigenesis and metastasis, which provides a potential therapeutic target for CRC patients.

Keyphrases

epithelial mesenchymal transition
cell proliferation
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
transcription factor
signaling pathway
patient reported outcomes