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Skin type specific photobiological response to visible light is mediated by constitutional melanin.

Hester Gail Y LimMichelle L KernsIsabelle D BrownSewon KangAnna L Chien
Published in: Photodermatology, photoimmunology & photomedicine (2022)
Skin types demonstrate unique biological responses to VL. The role of melanin in photoprotection is well-defined. However, given the pro-apoptotic function of nuclear MMPs, we suggest a potential mechanism by which melanin may mediate VL-induced phototoxicity.
Keyphrases
  • visible light
  • soft tissue
  • wound healing
  • anti inflammatory
  • cell death
  • high glucose
  • diabetic rats
  • drug induced
  • endothelial cells
  • risk assessment