Acute Kidney Injury Associates with Long-Term Increases in Plasma TNFR1, TNFR2, and KIM-1: Findings from the CRIC Study.
Ian Ellis McCoyJesse Y HsuJoseph V BonventreChirag R ParikhAlan S GoKathleen D LiuAna C RicardoAnand SrivastavaDebbie L CohenJiang HeJing ChenPanduranga S RaoChi-Yuan Hsunull nullPublished in: Journal of the American Society of Nephrology : JASN (2022)
Among patients with CKD, AKI during hospitalization was associated with increases in plasma TNFR1, TNFR2, and KIM-1 several months after their hospitalization. These results highlight a potential mechanism by which AKI may contribute to more rapid loss of kidney function months to years after the acute insult.