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In vitro and in vivo assessment of the proresolutive and antiresorptive actions of resolvin D1: relevance to arthritis.

Houda Abir BenabdounMerve KulbayElsa-Patricia RondonFrancis VallièresQin ShiJulio FernandesHassan FahmiMohamed Benderdour
Published in: Arthritis research & therapy (2019)
Our results provide additional evidence that RvD1 plays a key role in preventing bone resorption and other pathophysiological changes associated with arthritis. The study highlights the clinical relevance of RvD1 as a potential compound for the treatment of inflammatory arthritis and related bone disorders.
Keyphrases
  • rheumatoid arthritis
  • bone mineral density
  • bone loss
  • soft tissue
  • bone regeneration
  • postmenopausal women
  • body composition
  • combination therapy
  • risk assessment