Within- and across-network alterations of the sensorimotor network in Parkinson's disease.
Julian CaspersChristian RubbertSimon B EickhoffFelix HoffstaedterMartin SüdmeyerChristian J HartmannBenjamin SiglNikolas TeichertJoel AissaBernd TurowskiAlfons SchnitzlerChristian MathysPublished in: Neuroradiology (2021)
PD is accompanied by functional connectivity losses of the SMN, both, within the network and in interaction to other networks. The connectivity changes in short- and long-range connections are probably related to impaired sensory integration for motor function in PD. SMN decoupling can be partially compensated by dopaminergic therapy.