Nickel-Catalyzed Csp2-Csp3 Bond Formation via C-F Bond Activation.

Yee Ann HoMatthias LeiendeckerXiangqian LiuChengming WangNurtalya AlandiniMagnus Rueping

Published in: Organic letters (2018)

A nickel-catalyzed cross coupling of aryl fluorides via C-F bond activation has been developed. The alkylation method allows selective replacement of aryl fluorides by alkyl groups and enables the synthesis of diverse and otherwise difficult to access scaffolds in good yields.

Keyphrases

room temperature
reduced graphene oxide
transition metal
ionic liquid
carbon nanotubes
metal organic framework
gold nanoparticles
electron transfer