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Exposure to phenanthrene affects oocyte meiosis by inducing mitochondrial dysfunction and endoplasmic reticulum stress.

Yi WangSi-Hong LiShu-Jie YangXiao-Qing LiLu LiuXiang MaDong NiuXing Duan
Published in: Cell proliferation (2022)
Taken together, our study demonstrated that mitochondrial dysfunction and ER stress-induced oxidative stress and DNA damage are the major cause of poor oocyte quality after PHE exposure.
Keyphrases
  • endoplasmic reticulum stress
  • dna damage
  • induced apoptosis
  • oxidative stress
  • hydrogen peroxide
  • quality improvement