Tumor Immune Microenvironment Clusters in Localized Prostate Adenocarcinoma: Prognostic Impact of Macrophage Enriched/Plasma Cell Non-Enriched Subtypes.

Neil K JairathMark W FarhaSudharsan SrinivasanRuple JairathMichael D GreenRobert T DessWilliam C JacksonAdam B WeinerEdward M SchaefferShuang G ZhaoFelix Y FengIssam El NaqaDaniel E Spratt

Published in: Journal of clinical medicine (2020)

Distinct tumor immune clusters with a macrophage-enriched, plasma cell non-enriched phenotype and reduced plasma cell enrichment independently characterize an aggressive phenotype in localized prostate cancer that may differentially respond to treatment.

Keyphrases

prostate cancer
single cell
cell therapy
adipose tissue
radiation therapy
bone marrow